Can I put subs in with factory stereo and speakers?

I have a 1999 infiniti q45 with a bose factory sound system. I wanted subs until i found out how much of a pain it is. I have two 12" Rockford Fosgate powered by a Rockford Fosgate Punch P300-1 amp. Can i put those in my car with everything factory and still have it sound good. I think im going to also get a Scosche SLC4 Four-channel line output converter.